Tuesday, April 23, 2019

Is the use of placebos as a control ethical when an effective standard Essay

Is the aim of placebos as a promise ethical when an useful standard of cargon medication is available (YES or No) - Essay ExampleThis does not exclude the use of placebo, or no treatment, in studies where no prove prophylactic, diagnostic or therapeutic regularity exists.1iThe revision does not ban placebo still allows it only when thither is unanimous agreement among members of medical community that no powerful treatment is available. In the absence of effective preferred treatment, placebo controlled trials are permissible. In all other cases, its use has been restricted on ethical grounds. Critics be in possession of raised objections to the absolutism of the revised version. The basic ethical concern is grounded in one complex headland Are the rights of the subject more eventful than potential for greater good of the societyIf it is felt that inefficaciousness of drugs can be tried through placebos and new drugs can be developed, should the researchers proceed with t he trial or should they be concerned about welfare of the subjects to the extent that they abandon the research This is a question which decidedly is not easy to answer. Proponents of the revised version support the declaration that In research on man, the fire of science and society should never take precedence over considerations related to the well being of the subject.iiSupporters of placebo controlled trial are of the view that use of an inactive agent is preferable to an active one because it provides an important static reference pointiii. Another major argument in favor of placebo use is connected with food and Drug Administration in the US that does not approve any drug that has not been tested with placeboiv. While it is true that many resent the imperialistic stance of FDA, the fact remains that in around cases, clinical trials with placebo might appear to be the only option.It is true that welfare of the subjects is an important concern but equally important is the d evelopment of a better and more effective treatment. In case an effective treatment exists and the uncomplaining is suffering from a life threatening disease, it is better not to proceed with the placebo control method. But where a slight delay might not significant affect a patient and a clearly effective treatment is unavailable, use of placebo should be allowed unhindered. FDA on one occasion for typeface argued that the low risk to subjects justifies the use of placebo arms in clinical trials when effective treatments are available and chemical equilibrium is therefore impossible.vIt is possible to reach a consensus on the issue if we study the placebo control method carefully and delineate some clear rules as to when it can be applied. Emanuel, Miller offer a sound solution when they say, A placebo-controlled trial has a sound scientific rationale if the following criteria are met there is a high placebo-response rate the condition is typically characterized by a waxing-and- waning course, frequent oral remissions, or both and existing therapies are only partly effective or have very serious side effects or

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